Terbinafine HCl CAS:78628-80-5

Name:   Terbutaline

CAS:   78628-80-5

Synonyms:   TERBINAFINE HCL
                     TERBINAFINE HYDROCHLORIDE
                     (e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethylaminehydroc
                     lamosil
                     Terbinafine hdyrochloride
                     TerbutalineSulfateBase
                     Lamisil, N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1-naphthalenemethanamine
                     1-Naphthalenemethanamine, N-(2E)-6,6-dimethyl-2-hepten-4-ynyl-N-methyl-, hydrochloride
                     TERNBINAFINEHCL
                     Trebinafine hydrochloride
                    1-(3,5-Dihydroxyphenyl)-2-(tert-butylamino)ethanol

Molecular Formula:   C21H26ClN

Molecular Weight:   327.89

Appearance:   Crystalline Powder

Melting point:   204-208°C

mp:   204-208°C

storage temp.:   15-25°C

solubility:   methanol: soluble50mg/mL

form:   powder

color :   white

Usage:   An orally active, antimycotic allylamine related to naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis

Raw materials:   N-Methyl-1-naphthalenemethylamine hydrochloride

Description:   Terbinafine hydrochloride is the first orally active allylamine antifungal with 30-fold greater antifungal activity than naftifine. The compound is indicated for the treatment of ringworm and fungal nail infections. Terbinatine hydrochloride acts on a single fungal enzyme, squalene epoxidase, interfering with the biosynthesis of ergosterols in cell membranes. Unlike other antifungal agents, it does not inhibit cytochrome P450 enzymes.